If you read a book set somewhere you know do you prefer that? Or what about if it's somewhere you know but in the book you're reading it looks unrecognisable. "Hey that's not my town, that's not right!"
Here are a few thoughts of my own on setting.
If you want to use a real setting my best advice is to make it real. get the facts right and no one will complain, get it wrong and well, you'll certainly hear about it.
So do you like books set in real places or do you prefer created towns, cities and villages?